|
KMID : 0613820030130060896
|
|
Journal of Life Science
2003 Volume.13 No. 6 p.896 ~ p.902
|
|
|
Antiobesity Effects of Platycodon grandiflorum Extract on Body Weight Changes and Serum Lipid Profiles of Obese Rats Induced High Fat Diet
|
|
Byun Boo-Hyeong
|
|
|
Abstract
|
|
|
|
The present study was carried out to investigate the antiobesity effects of Platycodon grandiflorum extract on body weight changes and serum lipid composition of rats fed high fat diet. The Platycodon grandiflorum has been widely used as a folk food in the Orient for many centuries. We had experiment with Platycodon grandiflorum extract in order to find cure effects for obesty. The changes of the body weights in Platycodon grandiflorum extract treatment group showed a decrease in comparison with control group. Weekly body weights of PG group are respectively 243.7±2.0g, 283.5±4.3 g, 310.5±6.5 g, 333.2±7.5 g, 361.0±10.4 g, 390.5±11.5 g, 436.0±11.8 g, 454.4±11.4 g, 484.4±10.1 g. Body weight of PG groups are decreased compared with those of control group, but the rates are not significant. Total cholesterol of PG group(77.2±3.3 mg/dl) is decreased by 7.0% compared with that of control group. Serum triglyceride of PG group(103.6±9.0mg/dl) is decreased by 21.1% compared with that of control group. Serum free fatty acid of PG group(630.1±45.9 μEq/l) is decreased by 19.6% compared with that of control group. Total lipid amount of PG group(393.6±23.7 mg/dl) is decreased by 9.1% compared with that of control group. The above results suggest that Platycodon grandiflorum extract could prevent or cure metabolic diseases by preventing hyperlipemia caused by high fat diet.
|
|
|
KEYWORD
|
|
|
Body weight-regulation, Obesity, Platycodon grandiflorum, Serum, Lipid
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|